Ankylosing spondylitis refers to ankylosing spondylitis, and the survival time of a 20-year-old with ankylosing spondylitis is basically the same as that of a normal person, and the disease does not generally affect the length of life. The majority of cases of ankylosing spondylitis occur in young adulthood and are often insidious in onset, with rare cases occurring over the age of 40. In women, the disease progresses slowly and diagnosis is often delayed. Ankylosing spondylitis is a systemic disease that may be characterized by systemic symptoms such as fear of food, low-grade fever, malaise, weight loss and mild anemia. The course of ankylosing spondylitis is highly variable; it is characterized by self-resolving or exacerbating symptoms, and it is generally said that many patients have mild symptoms that resolve spontaneously. Patients may experience inflammation of the large surrounding joints, cervical spine ankylosis with severe hunchback deformity, but survive much the same as a normal person. The disease generally does not affect life expectancy, but can affect the patient’s normal life and work, and even cause disability. Prompt and proper treatment can reduce the risk of developing severe spinal and joint deformities. Early and standardized treatment is recommended after the development of ankylosing spondylitis to reduce the adverse effects of the disease.