HPV is human papillomavirus. There are many symptoms of oral infection with HPV, which can be mainly categorized into early symptoms and late symptoms. Early symptoms are not obvious, only surface changes, and later symptoms can affect eating as the condition becomes more serious. 1. Early symptoms: oral infection with HPV, early red papules can appear around the mouth, the overall papule texture is relatively soft, but also can show a granular, papillary changes, occurring in the perioral, sublingual, palate, gums and so on. 2. Late symptoms: with the development of the disease, the late papules can appear fusion, showing cauliflower-like, papillary, the surface can show gray, white, and even bleeding, vesicles and other phenomena, affecting the patient to eat. There are many symptoms of HPV infection in the oral cavity, and it is recommended to go to the hospital in time to complete the examination and take standardized treatment according to the doctor’s instructions.