Multiple polypoid lesions of the gallbladder are mainly related to chronic cholecystitis, gallbladder stones, cholesterol metabolism disorders and other causes. 1. Chronic cholecystitis: If the gallbladder is stimulated by chronic inflammation, it may cause proliferation of the gallbladder mucosa, causing the mucosa of the inner wall of the gallbladder and the submucosal layer to grow redundant organisms protruding into the inner lumen of the gallbladder, thus resulting in the appearance of multiple polypoid lesions of the gallbladder. 2. Gallbladder stones: bile contains too much cholesterol, bile pigment, etc., which may lead to cholesterol and bile acid-phospholipid concentration imbalance and cholestasis, which may also lead to polypoid lesions of the gallbladder. 3. Cholesterol metabolism disorders: cholesterol metabolism disorders may lead to high cholesterol concentration in bile, so that cholesterol deposition stimulates the proliferation of gallbladder wall, leading to the development of polyposis of the gallbladder. To summarize, patients with polyposis of the gallbladder need to rest more, do not overwork. Eat a light diet, avoid spicy and stimulating food. Moderate exercise, improve the body’s immunity.