Baldness in the middle of the head is usually considered as androgenetic alopecia or spot baldness, and the treatment methods include topical minoxidil application, oral finasteride, hair transplantation, injection treatment, etc. 1. Androgenetic alopecia: manifested as diffuse hair thinning, thinning, temporal, top of the head is obvious, hairline gradually moving back, can be used topical minoxidil cream, oral finasteride or spironolactone, as well as autologous platelet-rich plasma, low-energy laser treatment, etc., can improve the symptoms, and if the effect is unsatisfactory, hair transplantation can be considered. 2. Patchy baldness: manifested as patchy hair loss, with clear boundaries, smooth surface of the hair loss area, round or oval, can be used topically with minoxidil ointment, topical injections of tretinoin solution, oral glucocorticoids, cyclosporine and so on for serious cases, and in addition can be combined with photochemistry therapy, such as excimer laser, and so on. If there is baldness in the middle of the head, it is recommended to consult a doctor as soon as possible, after clarifying the condition, timely treatment, do not self-medication.