Patients can’t open their eyes, once they open their eyes, the pain and tears may be caused by corneal injury, eye foreign body, inverted eyelashes, etc. Patients can follow the doctor’s instructions to use medication, surgical treatment and other ways of treatment. 1. Corneal injury: because of trauma or corneal inflammation stimulation, patients with corneal epithelial defects, patients may appear eye pain, photophobia, tearing, difficulty in opening the eyes and other symptoms, patients can follow the doctor’s instructions to use bovine basic fibroblast growth factor drops and other medications, to promote the repair of corneal injury. 2. Ocular foreign body: If there is a foreign body in the conjunctival sac or on the surface of the cornea, under the stimulation of the foreign body, the patient may experience photophobia, tearing, difficulty in opening the eyes, and the patient needs to undergo a foreign body removal operation to remove the foreign body in time and relieve the discomfort of the eyes. 3. Inverted eyelashes: Inverted eyelashes patients because of the abnormal growth direction of the eyelashes, constantly rubbing the cornea, the patient may appear eye stinging, difficult to open the eyes of the discomfort symptoms. If the number of inverted eyelashes is small, you can use tweezers to remove them. If the number of inverted eyelashes is large and accompanied by entropion, surgical treatment, such as blepharoplasty, may be indicated. It is recommended that patients with eye pain and difficulty opening their eyes seek medical attention to evaluate their condition and follow their doctor’s instructions.