Need to identify the cause of toothache, toothache may be physiological, there may be pathological causes such as dental caries, pulpitis, periodontitis, gingivitis, etc., need to use medication or surgical treatment of the original disease, in order to alleviate toothache. 1. Physiological reasons: eating too hard or hot and cold food stimulation leads to toothache, which is mostly a temporary phenomenon and can be relieved by itself. 2. Pathologic causes: (1) Dental caries: mainly caused by bacterial infection, mainly manifested as toothache, tooth sensitivity, plaque on the teeth, oral odor. Analgesic drugs such as oral acetaminophen, ibuprofen, etc. can be used; at the same time, it is necessary to use resin filling for filling and repair. (2) Pulpitis and periapical inflammation: Pulpitis is the most common cause of toothache, and untreated pulpitis can cause periapical inflammation, both of which require root canal treatment. (2) Gingivitis: caused by poor oral hygiene, plaque and local foreign matter, manifested as toothache, bleeding gums when biting hard objects or brushing, usually using periodontal scaling, can quickly eliminate plaque and local foreign matter, relieve toothache; if necessary, combined periodontal scaling and local medication, such as the use of 3% hydrogen peroxide solution rinsing of gum pockets, to promote the demoralization of the inflammation. (3) Periodontitis: it can be manifested as red and swollen gums, loose teeth, etc. Generally, oral anti-inflammatory drugs can be used to treat, such as metronidazole, amoxicillin, etc., and if necessary, scaling, scraping, implantation, flap surgery, etc. can be used to improve the therapeutic effect. Symptoms of toothache, after self-relief is ineffective, should see a dentist in time to identify the cause, symptomatic treatment, the use of drugs need to comply with medical advice.