Typically a tetanus shot at $300 a shot is tetanus human immunoglobulin and the effect lasts for about 20 to 30 days. Usually patients need to have a tetanus antitoxin injection after a trauma if they are not allergic to tetanus antitoxin. If they are allergic they need to have a tetanus human immunoglobulin injection, which usually costs $300 a shot and is made from human serum, and usually the antibodies to the tetanus bacillus last for 20-30 days of immunity in the body. There are generally no adverse reactions to tetanus immunoglobulin, but a very small number of people may experience redness, swelling and pain at the injection site. It is contraindicated in people who are allergic to human immunoglobulin and selective IgA deficiency with anti-IgA antibodies. After the tetanus bacillus vaccine, patients should take good care of the wound to avoid premature exposure to water, which can form infection, and at the same time, they should carry out regular dressing changes and pay attention to local hygiene. If you feel unwell after the tetanus toxoid vaccine injection, you should seek medical checkup in time.