Azithromycin includes tablets, granules and capsules. Loratadine granules increase their concentration in plasma when combined with ketoconazole, macrolide antibiotics, cimetidine and theophylline and should be used with caution. Azithromycin is a macrolide antibacterial drug, so the two should not be taken together. Patients need to take the drugs correctly and reasonably according to their own situation and under the guidance of the doctor. 1. Loratadine granules are used to relieve the symptoms of allergic rhinitis, such as sneezing and runny nose, itchy nose and itchy eyes. It can also reduce the symptoms of chronic urticaria and other allergic skin diseases. There may be weakness, headache drowsiness, dry mouth, nausea, rash, and edema after taking the medicine. Rarely, there are adverse reactions such as blurred vision, blood pressure fluctuations, seizures, breast enlargement, hair loss, and allergies. Hypersensitivity to loratadine granules is contraindicated in lactating women. Caution should be exercised if there is a history of cardiac arrhythmia, renal insufficiency and pregnant women. 2. Azithromycin is used for the treatment of symptoms caused by a variety of sensitive bacterial infections, such as chronic bronchitis, community-acquired pneumonia, acute otitis media, acute bacterial sinusitis, pharyngitis, simple skin and skin infections, urethritis, cervicitis, male genital ulcers and so on. Adverse reactions such as nausea and vomiting, abdominal pain and diarrhea, palpitations, chest pain, dyspepsia, cholestatic jaundice, vaginitis, candidiasis, dizziness and headache, fatigue, rash, and itching may be experienced after taking azithromycin. It is contraindicated for those who are allergic to azithromycin, erythromycin, macrolides or ketolactones, those who have jaundice or hepatic insufficiency after using azithromycin. If you need to use the above two drugs, please consult a professional doctor and follow the doctor’s instructions for medication.