Hemodialysis after drug intoxication is risky and may cause complications such as bleeding, vascular access infection, muscle spasms, and narrowing of vascular access. 1. Bleeding, vascular pathway infection: when doing hemodialysis after drug poisoning, bleeding and vascular pathway contamination may occur, which may lead to infection caused by bacterial growth in the area. 2. Muscle spasms: when doing hemodialysis after drug poisoning, it may affect the blood circulation and cause muscle spasms due to ischemia of some muscles. 3. Narrowing of vascular pathways: When drug poisoning is used for hemodialysis, some of the vascular pathways may be blocked and narrowed. There are certain risks when doing hemodialysis for drug poisoning, but hemodialysis treatment has certain therapeutic effects on some drug poisoning patients. It is recommended that drug-poisoned patients go to regular hospitals in time and choose the appropriate treatment plan under the guidance of doctors.