ki67 high, to determine the treatment approach in conjunction with the cause of the disease, so as to reduce the index. Ki67 antigen is a kind of nuclear antigen of cell proliferation, mainly used to determine the proliferative activity of tumor cells, and has a close relationship with the degree of differentiation, infiltration or metastasis of tumors and prognosis, and is one of the important reference indexes for determining the prognosis of tumors. Chemotherapy is usually needed to treat the primary disease, and ki67 can only be reduced if the disease reaches remission or the tumor shrinks. For example, lymphoma patients with high ki67 can be treated with cyclophosphamide, vincristine, dexamethasone and other chemotherapy. Patients with acute myeloid leukemia with high ki67 need to be treated with chemotherapy with drugs such as cytarabine and zorubicin. When ki67 is high, you need to go to the hospital at the first time, combined with other laboratory tests and imaging results, to clarify the location and stage of the tumor, early diagnosis and treatment under the guidance of physicians.