Lodinexin, chemically known as Benadryl Hydrochloride Tablets, works to control blood pressure, improve myocardial remodeling, and improve the long-term prognosis of patients with heart failure. This drug is an angiotensin-converting enzyme inhibitor that inhibits the renin-angiotensin aldosterone system and can be used alone to lower blood pressure or in combination with other types of antihypertensive drugs for antihypertensive therapy. Because it can inhibit the aldosterone system, it also has a beneficial effect on the disease control of patients with heart failure, can improve the remodeling of the myocardium, and has a clear effect on the long-term prognosis. Oral administration should be careful to give small doses, and monitor blood pressure to adjust the dose, according to blood pressure, once or twice a day oral can be, common adverse reactions are headache and cough, as well as fatigue, nausea, edema and so on. The drug is contraindicated in case of allergy to the components of the drug, and contraindications include isolated kidney, bilateral renal artery stenosis and renal hypoplasia. The drug needs to be applied under medical supervision.