Patients with perianal moisture, may be caused by anal eczema, hemorrhoids, contact dermatitis and other diseases, patients can be directed by a doctor to use pimecrolimus cream, hemorrhoid cream, mupirocin ointment, etc. for treatment. 1. Anal eczema: anal eczema is a common skin disease in the anal area, patients can use non-hormonal ointment under the guidance of a doctor, such as tacrolimus ointment, pimecrolimus cream, etc.; hormonal drugs, such as tretinoin, etc.; anti-itching drugs, such as tretinoin econazole ointment, etc., for treatment, the patient can also use the aluminum acetate solution on the affected area for wet compresses to alleviate the symptoms of perianal humidity. 2. Hemorrhoids: for hemorrhoids caused by perianal moisture patients, can be used under the guidance of the doctor compound keratocyanate cream, Ma Yinglong musk hemorrhoid cream, skin hemorrhoid clear ointment and other topical medications for treatment. 3. Contact dermatitis: contact dermatitis is an inflammatory reaction caused by skin contact with certain exogenous substances, patients can use topical glucocorticoids under the guidance of a doctor, such as compound dexamethasone acetate cream, mometasone furoate ointment, etc.; topical antibiotic drugs, such as gentamycin hydrochloride ointment, mupirocin ointment, etc., a small amount of seepage, the available zinc oxide oil, etc., to treat, and improve the condition. It is recommended that patients strictly follow the doctor’s instructions for medication, do not change the dose of drugs or private abuse of drugs, pay attention to personal hygiene in life, to keep the perianal area clean and dry, usually pay attention to light diet, prohibit eating spicy, stimulating food.