When patients experience peeling and tingling of the skin after using Vicodin Cream, it is recommended that the medication be discontinued or, if needed, that the tolerance of Vicodin Cream be gradually increased. When using retinoic acid cream peeling and stinging skin, it is recommended to stop the drug and observe it first, in addition, when using it, it is recommended that patients use retinoic acid cream as much as possible spotting, applying a thin layer, and slowly increasing its tolerance. Secondly, patients are advised to use retinoic acid cream at bedtime. After waking up, it is recommended to wash the skin of any residual medication. In addition, if the patient does not feel uncomfortable after the first application of the drug on the skin for a period of time, then the second time, the drug can be appropriately prolonged. When patients use Vitamin A cream, if the skin appears uncomfortable feeling, it is recommended to go to the regular hospital in time for examination, under the guidance of professional doctors for treatment.