Fifth metatarsal base fracture needs to be treated with standardized treatment, such as reduction and internal fixation surgery, physical therapy, exercise therapy and so on. 1. Internal fixation surgery: After the fracture has been repositioned, microplates or screws can be used for internal fixation, which can help the fracture end to be well repositioned and promote healing. It should be noted that in the early stage of fixation, pay attention to the tightness of the bandage, observe the peripheral blood flow, and deal with it in time. 2. Physical therapy: when the patient has pain, ice therapy can be used, with a towel wrapped in an ice bag on the injured part of the ice every half an hour, which can effectively relieve the pain, and at the same time, the injured foot can be elevated, which is conducive to the return of blood flow and reduce edema. 3. Exercise therapy: when the metatarsal fracture to avoid weight-bearing, can be in the doctor’s advice to carry out rehabilitation training, sports wear good protective gear, to avoid collision caused by secondary injury. It is important to note that patients need to be treated in a professional institution and under the guidance of professionals for rehabilitation training. Rehabilitation requires a process, patients and their families should be patient and actively cooperate with the treatment.