Otitis media and herpes zoster have different pathogenesis, and there is no direct relationship between otitis media in childhood and herpes zoster in old age. Otitis media is an inflammation that occurs in the middle ear. The pathogen invades the middle ear through the Eustachian tube, causing the Eustachian tube to become congested and swollen, which leads to poor exudate outflow causing secretory otitis media or purulent otitis media. Oxyfloxacin ear drops can be used to treat otitis media as an anti-infective treatment, which may cause itching sensation, earache and other adverse reactions, and is contraindicated in allergic patients. Herpes zoster is caused by childhood chickenpox, resulting in chickenpox-herpes zoster virus latent in the body, when the adult immunity is low the virus is activated, and clusters of blisters, pain and so on. Herpes zoster requires timely use of antiviral treatment such as acyclovir tablets, which may cause dizziness, headache, thirst, insomnia and other adverse reactions, and is contraindicated in allergic persons. Therefore, getting otitis media as a child does not necessarily mean that you will get shingles when you get older. If you have otitis media or shingles, it is recommended that you consult a doctor in time and follow the doctor’s instructions to standardize medication and treatment to avoid the development of the disease.