Hidden pain in the middle of the upper abdomen with nausea may be caused by abdominal cold, gastritis, acute myocardial infarction, etc., and can be treated by abdominal warmth, oral omeprazole, and so on. 1. Cold abdomen: Cold abdomen can lead to abdominal pain and nausea, which can be relieved by wearing more clothes and applying hot compresses on the abdomen. 2. Gastritis: patients with gastritis can have vague pain in the middle of the upper abdomen with nausea and other symptoms, oral omeprazole, magnesium aluminum carbonate and other medications, while paying attention to a light diet. Adverse effects of omeprazole include headache, nausea, etc. Infants and young children and those who are allergic to the drug are prohibited. The adverse reactions of magnesium aluminum carbonate include constipation, lack of appetite, etc. It is forbidden for those who are allergic to this drug. 3. Acute myocardial infarction: patients with acute myocardial infarction may have epigastric pain, angina pectoris, nausea and other symptoms in the early stage, patients need to rest in bed, to reduce myocardial oxygen consumption through medicines such as metoprolol and through percutaneous coronary intervention to make myocardium get reperfusion. Metoprolol can be fatigue, headache and other adverse reactions, severe atrioventricular block is prohibited. All of the above medications should be used under the supervision of a physician and avoid self-medication. There are many other causes of vague pain in the middle of the upper abdomen with nausea, such as cholecystitis, pancreatitis, etc. If the above symptoms occur, it is recommended to go to the hospital in time for early and regular treatment.