Elevated ultrasensitive C-reactive protein needs to be treated with medications according to the cause of the disease, and the medications used for treatment are different depending on the cause of the disease. When the patient has an infection, such as urethritis or gastrointestinal infection, it will cause the patient’s C-reactive protein to be elevated, usually oral ceftriaxone, azithromycin, levofloxacin and other antibiotics, and gastrointestinal infections, if severe diarrhea occurs, loperamide and other antidiarrheal agents can be used to stop the diarrhea. Rheumatic diseases such as systemic lupus erythematosus patients, a variety of antibodies such as anti-nuclear antibody spectrum of the attack on the systemic systems, the patient will have a wide range of inflammation in various systems, causing C-reactive protein elevation, glucocorticoids are the first choice of drugs for the treatment of severe systemic lupus erythematosus, in addition to the use of immunosuppressants such as cyclophosphamide. Patients with myocardial infarction develop aseptic inflammation due to myocardial necrosis, and C-reactive protein is elevated in severe cases. It can be treated with absolute bed rest, interventional therapy, or pharmacologic therapy such as aspirin, clopidogrel, atorvastatin, and nitroglycerin. If patients find that the ultrasensitive C-reactive protein is elevated, they should consult a doctor in a timely manner, follow the doctor’s instructions to complete the relevant examinations to identify the cause of the disease, and choose the appropriate drug treatment. Patients should not take medication on their own, so as not to jeopardize their lives and health.