There is no most effective way to get rid of closed mouth on face, including general treatment, medication and laser treatment. Closed mouth on the face usually refers to closed acne on the face, which is usually related to the exuberant secretion of sebaceous glands and the blockage of hair follicle opening. 1. General treatment: usually pay attention to keep the skin clean, pay attention to light diet, etc., can reduce the phenomenon of closed mouth on the face. 2. Medication: Including retinoic acid drugs, such as retinoic acid cream, adapalene gel, etc.; can also be used regularly to improve the symptoms of acne with topical exfoliating chemicals such as fruit acid, salicylic acid, etc., to unclog keratinized hair follicles in order to reduce the incidence of acne. 3. Laser therapy: In the acute stage of acne, red and blue light therapy can be used to inhibit bacterial growth and promote wound healing. If you have too much closed acne on your face, it is recommended to go to a regular hospital and choose the appropriate treatment, and the use of the above medications should be in accordance with the doctor’s instructions.