How long it takes for a toothache to stop hurting after the nerve is killed generally varies from person to person. If a toothache is treated with a nerve extraction, the pain will usually be gradually relieved 1 to 2 days after the treatment is done. However, there are some patients who will not experience pain until 1 to 2 weeks after the treatment. 1. After receiving the nerve-killing treatment, the pain symptoms will be gradually relieved after 1~2 days due to the root canal preparation. However, if there are infected bacteria inside the tooth or the inflammation of the root tip of the tooth has not completely subsided, the pain symptoms of such patients will only slowly disappear 1~2 weeks after finishing the treatment. 2. Most of the toothache is caused by the fact that many people do not pay attention to the health of their teeth, which leads to the harm of dental caries due to bacterial growth, and even causes pulpitis and periapical inflammation, leading to severe toothache. 3. If the pain is still persistent, you can take some painkillers orally during the treatment period, such as ibuprofen extended-release capsules, you can also take antibiotics during the treatment period of 3 to 5 days to assist in the treatment, such as metronidazole, tinidazole, etc., which is more conducive to the healing of the disease. However, the medication should follow the doctor’s instructions. Therefore, patients should pay attention to oral hygiene habits, adhere to the habit of brushing in the morning and evening, rinse after eating, to ensure the health of the teeth, to reduce the chances of dental damage, dental damage should also be treated in time to avoid adverse effects.