Over-exertion legs pain can not be recovered, may be caused by certain diseases, such as muscle strain, pear-shaped muscle syndrome, lumbar disc herniation, knee arthritis and so on. 1. Muscle strain: When overworked, the leg muscles contract quickly and stretch excessively, exceeding the capacity of the muscles, which may lead to muscle tears or ruptures, which in turn leads to leg pain that cannot be recovered. 2. Piriformis syndrome: overwork may cause injury and spasm of the piriformis muscle, which compresses the sciatic nerve and causes sciatica, which may lead to unrecoverable leg pain, and even pain radiating to the foot. 3. Lumbar disc herniation: If the lumbar disc fibrous ring ruptures, the nucleus pulposus protrudes and compresses the nerves, which may lead to radiating pain or numbness in the legs. 4. Knee osteoarthritis: long-term exertion or old age, knee cartilage degeneration is serious, resulting in osteoarthritis of both knee joints, which may cause pain in the legs after exertion and cannot be relieved. In addition to the above mentioned diseases, leg thrombosis, rheumatoid arthritis and other diseases will also have overworked legs pain can not be restored symptoms, if a long time can not be relieved on their own, should be timely medical care, improve the relevant examination, clear the cause of the disease to give targeted treatment in accordance with the doctor’s instructions, so as not to delay the condition.