Whether blood uric acid 506μmol/L is serious or not varies greatly according to individual constitution, specific conditions and other factors, and it is necessary to further clarify whether there are complications, underlying diseases and other conditions, so it is not possible to make a generalization. A single test of 506 μmol/L cannot determine the presence of hyperuricemia, but a fasting blood uric acid test can be performed every other day, and if it is still higher than 420 μmol/L, hyperuricemia can be diagnosed. If the patient is accompanied by gout attacks, uric acid kidney stones, renal hypoglycemia and other complications, or coronary heart disease, hypertension, obesity, lipid metabolism disorders, stroke, cardiac insufficiency, diabetes mellitus or glucose intolerance and other underlying diseases, the condition is relatively serious. When the above complications and underlying diseases are accompanied by uric acid-lowering therapy, the underlying diseases and complications need to be actively treated at the same time. Patients with simple hyperuricemia have a relatively mild condition and do not need medication for the time being, but can regulate their blood uric acid level through dietary adjustments and lifestyle changes, such as eating a low purine diet, abstaining from alcohol, exercising appropriately, and increasing the amount of water they drink. It is recommended that patients go to the endocrinology department and rheumatology department of regular hospitals for detailed consultation, identify the causes and follow the doctor’s instructions for treatment.