Cold mouth herpes need to be resolved through medication and personal care and other methods. 1. medication: patients can follow the doctor’s instructions for external use of acyclovir cream, patients with serious symptoms can be under the guidance of the doctor with oral antiviral drugs, such as acyclovir, ribavirin and other drugs. 2. Personal care: patients need to maintain local cleanliness and hygiene, dry, avoid eating spicy stimulating food, appropriate exercise, enhance the body’s resistance to immunity, avoid picking, scratching lesions, eat more fresh fruits and vegetables, prohibit staying up late, pay attention to adequate sleep and rest, to reduce the symptoms of body fatigue, regulate the mood, and active treatment. It is recommended that patients go to the hospital in a timely manner, follow the doctor’s instructions for treatment, the application of drugs need to strictly follow the doctor’s instructions, do not self-medication.