There is no clinical cracked penis peeling skin with what medicine is good. Penile cracking and peeling is considered to be caused by local dry skin, clothing friction and other physiological factors, without special medication. Also consider with eczema, glans, etc., can follow the doctor’s instructions with glycerin lotion, erythromycin and other drugs. 1. Physiological factors: when the penis area skin dry, clothing repeated friction stimulation, easy to induce the penis cracking peeling. Usually there is no need for special treatment, daily skin care, try to wear cotton, loose underwear can be. 2. Eczema: If it is clearly caused by eczema, you can follow the doctor’s instructions to use local glycerine lotion, 3% boric acid solution, 0.1% ethacridine solution and other medications, but also follow the doctor’s instructions to use local dexamethasone cream, halomethasone cream and other glucocorticosteroids, tacrolimus ointment, pimecrolimus cream and other calcium-modulated neural phosphatase inhibitors; some patients can also follow the doctor’s instructions to take loratadine, cetirizine and other antihistamines, cyclosporine, thiazole, and other drugs. Some patients can also take antihistamines such as loratadine, cetirizine, cyclosporine, azathioprine and other immunosuppressants as prescribed by the doctor. 3. Glans: If it is clear that the bacterial infection is caused by, can follow the doctor’s instructions with boric acid water or isacridine solution to wash the penis glans, but also oral erythromycin, metronidazole and other antibiotic treatment. Candida infection can be treated with miconazole ointment, clotrimazole ointment, etc. Trichomonas glans patients can be rinsed with lactic acid solution, acetic acid solution. Penile dehiscence can also be caused by other factors and requires different treatment. It is recommended to go to a regular hospital for treatment of cracked penis and peeling skin, and strive for a speedy recovery.