Chronic renal insufficiency will have a decrease in glomerular filtration rate, and the decrease in glomerular filtration rate will lead to a decrease in the kidney’s ability to excrete toxins, and the phenomenon of elevated blood uric acid will occur. In addition, we also need to consider that chronic renal insufficiency patients themselves have hyperuricemia and gout, and even some renal insufficiency is caused by hyperuricemia. Normal human body produces and excretes relatively constant amount of uric acid every day. 100% of uric acid is filtered in glomeruli, 90% is reabsorbed in proximal tubules, and the rest enters into urine through renal tubules for excretion. When renal insufficiency occurs, glomerular filtration becomes abnormal, which can lead to elevated blood uric acid. As renal disease progresses, tubular reabsorption and excretion are also abnormal, which can lead to a further increase in the concentration of blood uric acid. In addition, it cannot be excluded that the patient himself is combined with hyperuricemia and gout, which can be mutually causative and continue to deteriorate and aggravate the progression of the disease. When the patient has elevated uric acid, must be low purine diet, appropriate intake of liquid, eat more fresh vegetables, kidney with high fructose drinks and fruits. Chronic renal insufficiency patients with high uric acid, it is recommended to go to the regular hospital in a timely manner, under the guidance of the doctor for comprehensive treatment.