Nasal bleeding in patients with liver cancer is mostly considered to be due to poor liver function, reduction of coagulation factors synthesized by liver and reduction of platelets, which will lead to coagulation dysfunction and further nasal bleeding, and after invasion of liver primary tumor, it will lead to necrosis of hepatocytes, which will further lead to poor liver function, and coagulation factors will be gradually reduced in the body of the patient. Some patients with viral hepatitis and cirrhosis will further develop hypersplenism and spleen enlargement, which will cause blood cell reduction, especially leukocyte and thrombocytopenia, and platelet reduction will cause coagulation dysfunction, causing subcutaneous petechiae, ecchymosis, and further nasal bleeding, oral bleeding, and intracranial hemorrhage. The patient needs active antiviral treatment and liver-protecting treatment, and can also consider a small amount of multiple transfusion of plasma and albumin for symptomatic supportive treatment, and after the liver function improves a little, the coagulation function will also improve accordingly.