Clinical diagnosis of hepatocellular carcinoma is as follows: 1) check the clinical history; 2) perform clinical examination: such as palpating obvious abdominal liver mass during physical examination; 3) perform imaging examination, the most commonly used and the simplest examination in clinic is ultrasound, and there are also other modalities, such as CT, nuclear magnetic resonance, hepatic angiography, etc.; 4) perform puncture biopsy of the liver where appropriate, i.e., perform the puncture under the guidance of ultrasound or CT, and perform the cytological examination for diagnosis. Liver cancer. Pathological examination helps to confirm the diagnosis, but there is a certain risk of puncture complications.5. Examination of hepatoma tumor markers is mainly used for the diagnosis of primary liver cancer, auxiliary examination of high-risk groups, census, liver cancer review, or metastasis monitoring.