Gallbladder layered-like changes are mostly caused by cholecystitis, which can be treated with anti-inflammatory and choleretic drugs. 1. Anti-inflammatory drugs include: cephalosporin antibiotics, penicillin antibiotics, nitroimidazole antibiotics, fluoroquinolone antibiotics, etc. The representative drugs are cefixime, cefotaxime, amoxicillin, penicillin V potassium, metronidazole, tinidazole, levofloxacin, ciprofloxacin and so on. 2. Choleretic drugs are: ursodeoxycholic acid, adenosylmethionine and so on. The above drugs have different degrees of adverse reactions, such as gastrointestinal reactions, allergies, liver and kidney function impairment and other adverse reactions. When taking these drugs for treatment, they must be taken under the guidance of a doctor in strict accordance with medical advice.