Perianal abscess dressing change is more painful, especially deep perianal abscess, dressing change pain will be more intense. Perianal abscess, also known as perirectal abscess, is an acute purulent infectious disease that occurs in the soft tissues around the rectum and anal canal or in the interstitial area around it, and its clinical manifestation is a small lump around the anus, with sudden severe pain, accompanied by localized fever, uneasiness, feeling of rectal swelling, chills, etc. The pain is more sensitive because of the rich sensory nerves around the anus. Due to the rich sensory nerves around the anus, the pain is more sensitive, usually perianal abscess dressing change is more painful, especially the deeper abscess, dressing change pain will be more intense. Patients can take painkillers, such as ibuprofen, celecoxib, etc., and antibiotics, such as cefoperazone, metronidazole, levofloxacin, etc., under the guidance of the doctor for anti-infective treatment to alleviate the condition. For more serious conditions and conservative treatment is not obvious patients, surgery can be carried out. It is recommended that patients strictly follow the doctor’s instructions, actively cooperate with the doctor’s treatment, pay attention to the care of the affected area, pay attention to perianal cleaning, to avoid infection, to maintain a smooth bowel movement, regular defecation, to avoid prolonged sitting when defecating, and so on.