There are no contraindications to performing a nucleic acid test, only a few precautions. The nucleic acid test is used to check for viral infections and is usually done by taking a throat or nasal swab. Hygiene of the mouth and nose is required before the test, and a mask is also needed. In addition, there are other tests such as sputum, genital secretions, blood, feces, urine, etc. The precautions are not exactly the same, so it is recommended to consult with your doctor or testing center in advance. 1. Maintain oral and nasal hygiene: Pay attention to keeping the oropharynx and nasal cavity clean so as not to cause inconvenience in sampling or affect the test results. Smoking, drinking or eating a lot of food are not recommended near the time of sampling, and you can rinse your mouth properly with water. Taking a throat swab may cause nausea and dry heaving in some people, so do not eat too much before the test so as not to induce vomiting on a full stomach. 2. Wear a mask: wear a mask before and after the nucleic acid test. Nucleic acid test usually produces a gathering of people, in order to avoid cross-infection, it is recommended to wear a good mask before and after the nucleic acid test.