Pancreatic cancer is a kind of malignant tumor of digestive tract with insidious onset, rapid progression, extremely poor treatment effect and prognosis. Pancreatic cancer has an insidious onset and early diagnosis is difficult, and most of the patients have already belonged to middle and late stage when diagnosed. Depending on the location and size of the tumor, the affected organs and its severity, pancreatic cancer patients may show epigastric or back pain, nausea, abdominal distension, jaundice, new-onset diabetes mellitus, weight loss, and change of stool properties, etc. Occasionally, patients with acute pancreatitis as the main manifestation. Pancreatic cancer compresses the bile ducts, leading to the obstruction of the bile duct system, bile can not be discharged, which leads to increased pressure in the capillary bile ducts and bile ducts and rupture, and bilirubin reflux into the bloodstream, thus pancreatic cancer is mainly characterized by elevated bilirubin binding. If pancreatic cancer is suspected or diagnosed, it is recommended to go to a regular hospital for a comprehensive assessment of the condition and follow the doctor’s instructions for treatment, so as to avoid delaying the condition.