Men who have just contracted syphilis may show symptoms of a hard chancre. Syphilis is a sexually transmitted disease caused by infection with the spirochete syphilis. Men who have just been infected with syphilis may show symptoms of a hard chancre, which is a painless ulcer with cartilage-like hardness on palpation that appears on the external genitals and perianal and other skin and mucous membrane areas, most of which are solitary and may subside on their own. Men infected with syphilis can be treated with penicillin drugs under the guidance of a doctor, such as benzylpenicillin, procaine penicillin, etc., if penicillin allergy can be selected ceftriaxone sodium and other drugs. Men who have just contracted syphilis may also have no obvious clinical manifestations. If you have high-risk behaviors worried about the infection of syphilis spirochetes, you should actively consult a doctor for a clear diagnosis, so as not to delay the condition.