Bleeding spots on the face from taking clopidogrel can be temporarily observed, and if the condition is particularly serious, the dosage can be gradually reduced or discontinued. The main effect of clopidogrel is to inhibit ADP receptors in the body, and it has an inhibitory effect on platelets, which can be clinically used in the treatment of ischemic cardiovascular and cerebrovascular diseases, such as cerebral thrombosis and myocardial infarction. The adverse reactions of clopidogrel are skin and mucous membrane bleeding, for patients with mild skin and mucous membrane bleeding, there is no need to stop the drug, observe the change of condition. The dosage can be reduced if the symptoms are obvious, and the drug should be stopped if it is particularly serious to prevent serious adverse reactions. Adverse reactions of clopidogrel include nausea, vomiting, stomach pain, gastric distension, skin mucosal bleeding, gastrointestinal bleeding, cerebral hemorrhage, etc. It is contraindicated for patients with allergy to the drug components, active bleeding, active ulcers and so on. If bleeding spots on the skin and mucous membranes appear during oral administration of Clopidogrel, it is necessary to promptly communicate with the doctor and decide on the adjustment of the treatment program.