Dry and painful nose, common causes are dry rhinitis, atrophic rhinitis, nasal vestibulitis, etc. Specific medication needs to be based on different causes of the appropriate choice, you can follow the doctor’s instructions to use nasal drops, antibiotics and other drugs. 1. Dry rhinitis: If the environment is too dry, there are abundant capillaries in the nasal cavity, which may cause bleeding of the mucous membrane of the nasal cavity, accompanied by pain. Patients can use saline to rinse the nasal cavity appropriately, and at the same time can follow the doctor’s instructions to use compound menthol nasal drops to moisturize. 2. Atrophic rhinitis: due to the nasal cavity by some irritating factors caused by dry nose, dry pain, dry scabs and so on. Patients can follow the doctor’s instructions to use hexenestrol oil or streptomycin liquid nasal drops to relieve symptoms. 3. Nasal vestibulitis: nasal secretions will stimulate the nasal mucosa to produce inflammation, inflammation stimulation to the nasal vestibule, and then make the nose feel dry. Patients can follow the doctor’s instructions to use erythromycin ointment, polymyxin B ointment and so on to carry on the treatment. If the symptoms of dry and painful nose persist, it is recommended to go to the hospital for a clear diagnosis and standardized medication and treatment to avoid delaying the condition.