Non-keratinizing undifferentiated carcinoma is a malignant tumor with a high degree of malignancy. Undifferentiated carcinoma is a malignant tumor that occurs in the epidermis or cells of the appendages, and usually develops in the skin, oral cavity and other areas covered by squamous epithelium. The degree of malignancy is judged according to the degree of differentiation of the tumor, which is generally classified as highly differentiated carcinoma, moderately differentiated carcinoma, undifferentiated carcinoma and poorly differentiated carcinoma. The higher the degree of differentiation, the lower the malignancy of the tumor, the better the treatment effect and the longer the average survival time of the patient; the lower the degree of differentiation, the higher the malignancy of the tumor, and it is also easy to spread and metastasize. Undifferentiated cancer is the type with the highest degree of malignancy. If early detection, early diagnosis and early treatment are possible, early undifferentiated cancers can still be treated well through active treatment and surgical resection. Early detection, early diagnosis and early treatment are the keys to curing cancer and prolonging life.