Children’s cough with sputum can be caused by acute upper respiratory tract infection, can also be caused by allergic asthma, in addition to reflux esophagitis can also lead to children’s cough with sputum; can be taken to the general treatment and aminoglutethimide oral solution and other medication to improve the treatment. 1. Acute upper respiratory tract infection: acute upper respiratory tract infection is a high incidence of children coughing with sputum, daily attention to warmth, eat a light diet, drink plenty of water, cough and sputum can take Ambroxol and other drugs. 2. Allergic asthma: In addition to coughing up phlegm, children with allergic asthma also have wheezing, and some of them have low-grade fever. Need to avoid contact with allergens. Mainly take budesonide, terbutaline and other nebulizer treatment, combined with oral phlegm medicine treatment. 3. Reflux esophagitis: Reflux esophagitis can cause the child to cough like clearing the throat and have phlegm in the throat. Omeprazole can be taken to inhibit gastric acid secretion. Children coughing with phlegm may also be caused by pneumonia. It is recommended to go to the hospital in time, improve the examination to clarify the cause of the disease, and then give targeted treatment or treatment. All of the above medications should be used under the guidance of a doctor.