Skin peeling on the wrists and ankles of newborn babies may be due to a reaction to the fetal fat that develops just after the fetus is born. Especially after the baby is born, due to the baby’s own hormones brought from the mother, this hormone has estrogen and androgen. In particular, if the androgens are too strong, there may be a reaction of the body after birth. One of the main reactions may be seborrhea, which in some babies occurs in the wrists and ankles. Excessive seborrhea in this area can lead to mild localized hyperplasia of the stratum corneum, which can lead to peeling due to maceration or friction.