Cytomegalovirus and Rubella virus, herpes simplex infection at the same time will show symptoms such as fever, rash, hepatosplenomegaly and persistent jaundice, etc. It is recommended to go to the hospital promptly after diagnosis and receive treatment according to the symptoms. 1. Fever and rash: Cytomegalovirus and rubella virus, herpes simplex infection at the same time will stimulate the immune system, resulting in enlarged lymph nodes, which in turn will manifest symptoms such as fever and rash. 2. Enlarged liver and spleen, persistent jaundice: Simultaneous infection with cytomegalovirus and rubella virus, herpes simplex can lead to liver damage, which in turn manifests symptoms such as enlarged liver and spleen, persistent jaundice. Cytomegalovirus and rubella virus herpes simplex infection at the same time will show symptoms such as fever, rash, hepatosplenomegaly and persistent jaundice, etc. It is recommended to go to the hospital for treatment promptly after diagnosis.