Most cases of short bowel syndrome in newborns can be cured with aggressive surgical treatment. Short bowel syndrome occurs in newborns usually as a result of developmental abnormalities. In most cases, it can wait until the baby is born and can be treated surgically to help the baby recover, but it may lead to problems with the function of the small intestine in absorbing nutrients. In the long term, this can produce problems such as absorption disorders and growth retardation. Therefore, when short bowel syndrome is found in newborns, after surgical treatment, a reasonable post-care plan needs to be formulated according to the newborn’s surgical condition and nutritional status, and increased nutrition and prevention of infection can improve the cure rate. Overall, after the discovery of short bowel syndrome in newborns, after active surgical treatment, a more satisfactory prognosis can be achieved, but the specific recovery is closely related to the quality of postoperative care, and whether it can get adequate nutritional supply. Parents are advised to pay attention and take care of their newborns scientifically under the guidance of their doctors in order to improve their recovery after treatment.