The alkaline phosphatase index in liver function tests is mainly used for the diagnosis and identification of hepatobiliary diseases. High alkaline phosphatase may be a normal phenomenon, or it may be due to life factors such as long-term alcohol consumption, or disease factors such as skeletal diseases, hepatobiliary diseases, etc., which require some attention. 1, the normal physiological phenomenon of specific people: children in the bone development period, usually 1-2 times higher than the normal adult alkaline phosphatase activity. In addition to this, pregnant women or adolescents who consume foods with high fat content may also have elevated alkaline phosphatase, which is not a cause for excessive concern. 2, lifestyle factors: If the high alkaline phosphatase is not serious, it may be caused by excessive alcohol consumption or excessive obesity, and patients need to develop healthy lifestyle habits, reduce alcohol consumption, eat a light diet, and strictly control their weight. 3, disease factors: Diseases of the hepatobiliary system such as jaundice, cirrhosis, viral hepatitis, etc., can lead to high alkaline phosphatase in liver function tests. In addition to hepatobiliary diseases, rickets, malignant bone tumors, bone metastases from malignant tumors and other bone diseases, and systemic diseases such as hyperthyroidism can also show high values of alkaline phosphatase. Therefore, if there is a high value of this indicator, other values of liver function should be observed simultaneously and the relevant tests should be further improved. The presence of high alkaline phosphatase should be actively addressed both in terms of adjusting lifestyle habits and treating related diseases to avoid other negative consequences.