Sweating and peeling of the skin on the hands can cause fingerprints to become lighter or disappear, which may be a physiological phenomenon or a pathological phenomenon. 1. Physiological phenomenon: when washing hands excessively, contact with certain chemicals, do more housework, may lead to particularly dry skin, will appear peeling phenomenon. 2. Pathological phenomenon: some diseases of the hand may lead to hand sweating and peeling, such as hand eczema, may be related to physical, allergic and other factors, often manifested as blisters, peeling, itching, etc.; fungal infections can also lead to erythema, blisters, peeling and itching, etc.; hereditary keratosis pilaris, there will be peeling phenomenon. Finger peeling phenomenon may have other reasons, it is recommended to go to the hospital in a timely manner, under the guidance of the doctor for treatment, do not blindly deal with their own. Daily attention to protect hands, avoid contact with irritating objects.