When glaucoma has high intraocular pressure at night, it can be treated with medication, surgery, laser and other methods under the guidance of a doctor. 1. Medication: When glaucoma patients have high intraocular pressure at night, they need to do 24-hour monitoring of intraocular pressure fluctuation under the guidance of doctors, and follow the doctor’s instructions to use travoprost eye drops, bemeprost eye drops and other medications for treatment. 2. Surgery: For patients who have unsatisfactory effect of medication or more serious condition, trabeculectomy, atrial angulotomy and other surgical methods can be adopted for treatment. 3. Laser treatment: It can cause the burning of smaller tissues in the eye, so that the beam of light is focused on the eye for treatment, thus achieving the purpose of treatment. Glaucoma patients with high intraocular pressure at night, it is recommended to consult a doctor for examination in time to avoid delaying the condition and affecting vision.