Alisatanate is one of the commonly used antihypertensive drugs used in clinical practice with the following advantages and disadvantages. The advantages are that it does not affect the liver and has little kidney damage; the disadvantages are that side effects such as headache, dizziness, and vascular system symptoms can occur. The advantages of Alisatan ester are as follows: 1. Does not affect the liver: after taking the drug, it does not pass through the liver, but directly enters the bloodstream, and can be distributed to the whole body to play the effect of lowering blood pressure, so it does not hurt the liver; 2. Less renal damage: about 15% of the drug is metabolized by the kidneys, so it can be used safely in patients with hepatic and renal insufficiency, and most of it is excreted in the bile and feces; 3. Reduce uric acid: hypertensive patients may be combined with high uric acid, alisatan ester can slightly reduce uric acid while lowering blood pressure; 4. Other: Alisatan ester has no adverse effect on blood lipids, blood glucose, blood potassium, blood sodium, blood chloride indicators, will not cause high blood fat, high blood sugar phenomenon, hypertension combined with diabetes mellitus, hyperlipidemia can be safely taken. The disadvantages of alisatan ester are as follows: 1. The most common side effects of alisatan ester tablets are symptoms such as headache, dizziness, fever and fatigue. 2.Some patients experience abnormalities of the cardiovascular system, characterized by increased heart rate and panic, and some patients also experience low back pain, sore knees and leg pain. 3. Alisatan ester can also cause nasal congestion, cough, sneezing, runny nose, upper respiratory tract infections, etc. A few patients have itchy skin and herpes on the lips and mouth and the medication should be stopped immediately. Patients with serious discomfort, abnormal liver and kidney function indicators, etc., please consult a doctor immediately, patients must consult a doctor before using the drug, according to medical advice.