Knee pain plastered more pain may be related to the timing of the use of plaster unreasonable, adverse drug reactions and other reasons. 1. The timing of use is unreasonable: most of the popular plasters on the market are mainly based on proprietary Chinese medicines, whose main role is to expand local blood vessels and promote blood circulation. Most of the patients with knee pain are in the acute stage of the disease, and the use of ointment at this stage may lead to further aggravation of the disease exudation and edema, and the condition will be heavier rather than lighter after the use of ointment. 2. Adverse drug reactions: some patients who are allergic to the components of the ointment or patients with allergies, the use of ointment may appear in the affected area of hives, itching, localized ulceration and other adverse reactions, aggravating the damage. In addition, the use of ointment for more than 24 hours may lead to local skin damage, reactive dermatitis and other manifestations, may also lead to further aggravation of the condition. If the symptoms of knee pain are not relieved, or accompanied by other symptoms, you should go to the hospital in a timely manner, after clarifying the cause of targeted treatment.