There is still a risk of recurrence of H. pylori after treatment. Recurrence is mainly related to the development of drug resistance and failure to take medication as prescribed by the doctor. 1. Development of drug resistance: H. pylori resistance to the antibiotics used is the main reason for treatment failure. The eradication rate of H. pylori is significantly lower among retreatment patients than among first-time patients, and the higher the density of H. pylori, the more likely the treatment will fail. 2. Failure to comply with the doctor’s instructions to take medication: because of the side effects of the drug patients do not tolerate, or patients forget, can not be on time, according to the amount, full course of treatment to adhere to the medication to the cure, thus resulting in the eradication of failure. If the patient recurrence of Helicobacter pylori, should consult a doctor in a timely manner, according to the doctor’s instructions, according to the amount, according to the course of medication, and do not eat spicy and stimulating food, dishes should be disinfected often, if necessary, to take separate meals, so as to avoid relapse after the cure.