The effect of immunotherapy for liver cancer is generally the enhancement of patient’s immune function. Immunotherapy is often an auxiliary treatment for surgical treatment, which can effectively kill the tumor cells left over from surgery and reduce the number of tiny residual foci. Immunotherapy is to enhance the immunity of human body, activate the body’s immune system, effectively remove the lesions in the body of post-surgery or middle-late stage patients who cannot undergo surgery, activate the immune cells to kill the tumor cells, and effectively control the development of hepatocellular carcinoma. At present, the immunosuppressants commonly used in clinic are PD-1 and PD-L1, which can effectively enhance the immunocytes to re-recognize and kill the liver cancer cells, and will not affect the other normal cells in human body. Immunotherapy for liver cancer is mostly used as an auxiliary treatment, which needs to be combined with surgery, radiotherapy, chemotherapy and other comprehensive treatments, and needs to be actively treated under the guidance of doctors.