Creatinine, generally considered to refer to blood creatinine, creatinine 370μmol/L is more serious and needs to be actively treated. Generally, the normal value of blood creatinine for adult male is 53~106μmol/L; the normal value of blood creatinine for adult female is 44~97μmol/L. Therefore, blood creatinine 370μmol/L, no matter male or female, is seriously high. It is generally considered to be related to renal disease, which can be categorized into acute renal failure and chronic renal failure. Clinical symptoms may include lower limb edema, fatigue, nausea, vomiting, breathlessness, and oliguria or anuria. Drugs or renal replacement therapy should be prescribed. This condition is generally more serious and may affect the patient’s life expectancy if not treated actively and effectively. For patients with elevated creatinine, it is recommended to go to regular hospitals as soon as possible for examination, clear diagnosis, and receive treatment under the guidance of specialists to avoid delaying the condition and affecting the health of the body.