Patients who are ready to undergo bile preservation should be in a healthy psychological state and have a full understanding of the consequences of bile preservation. The current medical level cannot guarantee that gallbladder preservation will not recur after removal of stones or polyps. Also any patient with biliary preservation must be psychologically prepared for intraoperative or postoperative distant need for gallbladder removal with good gallbladder function with good contractile function and reserve bile function. Good gallbladder function measurements. Gallbladder stones with short history, no or mild symptoms and low frequency of attacks are suitable for biliary preservation. Simple cholesterol polyps can be bile preserved. Single stones or multiple stones of similar size are less likely to recur; multiple small stones or clay stones are prone to recurrence or residual. Gallbladder enlargement and gallbladder atrophy are not recommended for biliary preservation. Gallbladder polyps depend on the number of polyps, their growth and intraoperative pathological results to decide the removal or preservation of gallbladder. Gallbladder stones combined with polyps are not recommended for biliary preservation. Biliary preservation is not recommended for stones secondary to pancreatitis. Long medical history, severe thickening and grossness of the gallbladder wall are not recommended for biliary preservation. Biliary preservation is not recommended for gallbladder in the acute inflammatory phase. Gallbladder neck polyps are not recommended for biliary preservation. Gallbladder preservation is not recommended for patients over 50 years of age, or patients with severe cardiovascular disease or diabetes. Bilateral signs of the gallbladder, septicemia, gangrene, perforation of the gallbladder, inflammatory encapsulation, stone impaction in the neck of the gallbladder or gallbladder duct are not recommended for biliary preservation. Porcelain gallbladder and gallbladder cancer cannot be excluded. Gallbladder duct obstruction and “white bile” in the gallbladder cannot be preserved. Adenomyosis of gallbladder, adenomatous polyps of gallbladder cannot preserve gallbladder. Gallbladder interstitial stones cannot be preserved.