A layer of oil seems to float on top of the urine may be caused by dietary factors, kidney disease, celiac disease and other factors, and should be based on the patient’s medical history, clinical manifestations, laboratory tests and other comprehensive judgment. 1. Dietary factors: prolonged consumption of greasy food may lead to more lipids in the urine, which may cause a layer of oil on the surface of the urine. Generally, there are no other clinical symptoms, and the patient’s diet should be adjusted, and he should drink more water and urinate more, which will generally return to normal on his own. 2. Kidney disease: for example, glomerulonephritis, may lead to abnormalities in the filtration function of the kidneys, it will make the urine surface there is a strange substance, manifested as a layer of oil floating on the top of the urine, while patients are often accompanied by swelling of the lower limbs, proteinuria and other symptoms. 3. Celiac disease: usually associated with filariasis infection, when the infection is more serious, can lead to lymphatic vessel blockage, there are many lymphatic fluids will enter the urine, will make the urine appear a layer of oil, may also be accompanied by fatigue, fever and other symptoms. The urine seems to float above a layer of oil, it is recommended that the regular hospital medical treatment, improve the relevant examination, the corresponding targeted treatment.