As early as 2000 B.C., China has already recorded the use of iron heating to cure cancer; in 1893, Coley used dentin toxin to induce hyperthermia to treat 17 cases of inoperable sarcoma, 7 of which were cured; in 1909, Schmidit firstly proposed that local heating could make tissues more sensitive to radiation …… After nearly 20 years of scientific research After nearly 20 years of scientific research, thermotherapy has become an independent and effective treatment for tumors. Heat therapy refers to the treatment method of using biophysical methods to increase body temperature or local heating to change the environment in which tumor cells are located and cause their denaturation and necrosis, so as to inhibit and prevent cancer recurrence and metastasis. Meanwhile, both in vitro and clinical practice have proved that heat therapy can increase the therapeutic effect of radiotherapy and chemotherapy, so heat therapy occupies an important position in the comprehensive treatment of tumors. The normal tissues of human body under the condition of elevated body temperature, blood vessels expand, blood flow accelerates and heat dissipation is faster. Due to this regulating effect of the body, it ensures that when the body temperature rises, even when the body temperature reaches 41.5~43℃, the tissue is not damaged much and can be repaired. However, this is not the case for tumor tissues. The blood vessels in tumors have abnormal morphology, are disorganized and twisted, easily distorted by pressure, and form thrombosis or embolism. In addition, the blood vessels in the tumor are mostly composed of monolayer cells, which are fragile and easily broken. As these new blood vessels are underdeveloped and deformed, they lose their self-regulating effect after heat, and the veins cannot speed up the reflux, so the local blood stagnation in tumor is only 1%-15% of normal tissue, which makes it difficult for tumor tissue to dissipate heat and increase the temperature. The temperature of malignant tumor tissues is often higher than that of adjacent normal tissues by 8~10℃. In the same way, if the normal tissue temperature is increased to 40℃, the temperature inside the tumor can be increased to about 48°C. This temperature is enough to kill the tumor cells by heat, but the normal tissue is not damaged. Generally speaking, the larger the tumor, the lower the blood flow, and the better the effect of heat therapy.