According to Chinese medicine, obese patients mostly have phlegm and dampness, dampness and heat, spleen and kidney yang deficiency, and qi stagnation and blood stasis. Minimally invasive buried thread for weight loss is based on the meridian theory of Chinese medicine and is a development of the acupuncture treatment mode, in which a special degradable thread is buried in acupuncture points to obtain a long-lasting acupuncture stimulation method. After the treatment, the thread will be softened, decomposed, liquefied and absorbed in the body, producing continuous physiological, physical and biochemical stimulation to the acupuncture points. Patients who have lost weight through acupuncture have been clinically observed to have their appetite suppressed and their digestion and absorption controlled, resulting in a reduction in caloric intake [1]. This may be related to the ability of acupuncture to activate the satiety center, which increases the level of excitation of the satiety center and inhibits the active effect of the hunger center. It has also been found that acupuncture can also regulate the abnormal NE, DA, 5-HT, and 5 HIAA levels in the feeding center and normalize them. Therefore, minimally invasive buried threads have the potential to act on hypothalamus-pituitary-adrenal, thyroid, and gonadal axis functions through reasonable point formulations to suppress appetite, regulate fat metabolism, enhance energy metabolism, and achieve weight loss. Synthetic absorbable sutures are buried threads based on polymer materials such as polyethylene glycol (PLA) and polyethylene propylene glycol copolymer (PGLA), which are mostly absorbed by the body through the action of hydrolytic enzymes in the body, so they are quite safe and have the advantages of controllable stimulation intensity and time, small tissue reaction and good absorption. The polymer threads used in minimally invasive buried threads not only avoid the disadvantages of lamb’s intestine threads that are easily infected and allergic, but also allow the stimulation of acupuncture points for up to two weeks or longer. This method not only reduces the pain and number of visits to the patient for acupuncture treatment, but also achieves the requirements of convenience, minimally invasive, effective and controllable.